HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE

HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE - Names and Identifiers

Name	4-Perhydroazepinone hydrochloride
Synonyms	4-PerhydroazepinoneHCl azepan-4-one hydrochloride HEXAHYDRO-4H-AZEPIN-4-ONE HCL PERHYDROAZEPIN-4-ONEHYDROCHLORIDE 4-Perhydroazepinone hydrochloride 4-PERHYDROAZEPINONE HYDROCHLORIDE Hexahydro-4-azepin-4-one hydrochloride HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE Hexahydro-4H-azepin-4-one hydrochloride 4-PERHYDROAZEPINONE HYDROCHLORIDE HEXAHY 4H-AZEPIN-4-ONE, HEXAHYDRO-, HYDROCHLORIDE 4-PERHYDROAZEPINONEHYDROCHLORIDEHEXAHYDRO-4-AZEPIN-4-ONEHYDROCHLORIDE
CAS	50492-22-3
InChI	InChI=1/C6H11NO.ClH/c8-6-2-1-4-7-5-3-6;/h7H,1-5H2;1H

HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE - Physico-chemical Properties

Molecular Formula	C6H12ClNO
Molar Mass	149.62
Melting Point	176-181℃
Flash Point	152°(306°F)
Appearance	Crystalline powder
Color	White to Orange to Green
Storage Condition	Inert atmosphere,Room Temperature
MDL	MFCD02183487

HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R20/22 - Harmful by inhalation and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/39 -
WGK Germany	3
Hazard Note	Irritant

HEXAHYDRO-4H-AZEPIN-4-ONE HYDROCHLORIDE - Introduction

4-Perhydroazepinone hydrochloride is an organic compound with the chemical formula C6H13NO · HCl, also known as 4-PHA hydrochloride. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless crystal or white powder
-Melting point: approx. 90-94°C
-Solubility: Soluble in water and alcohol solvents, slightly soluble in ether solvents

Use:
4-Perhydroazepinone hydrochloride is commonly used as a synthetic intermediate or catalyst in chemical research. Its main applications include organic synthesis, pharmaceutical research and agricultural chemistry.

Preparation Method:
4-Perhydroazepinone hydrochloride can be prepared by the following steps:
1. reacting 1,6-hexanediamine with acetic anhydride to generate N-acetyl hexamethylene diamine;
2. reacting N-acetyl hexamethylene diamine with thionyl chloride to generate N-[2-(sulfoxide) ethyl]-1,6-hexamethylene diamine;
3. N-[2-(sulfoxide) ethyl]-1,6-hexanediamine is hydrogenated with hydrogen in the presence of a catalyst to prepare 4-azepinone.
4. 4-Azazepinone reacts with hydrochloric acid to form 4-Perhydroazepinone hydrochloride.

Safety Information:
4-Perhydroazepinone hydrochloride is a general organic compound and should comply with routine laboratory safety procedures and hazardous material handling procedures. It may be irritating to the eyes, skin and respiratory system, so appropriate protective measures should be taken during operation, including wearing gloves and respiratory protective equipment. In addition, it is also a toxic substance and should be stored properly and kept away from flammable and explosive substances. As the properties of the compound may be affected by factors such as preparation method and purity, detailed safety information from the supplier should be consulted before actual use.

Last Update：2024-04-09 21:04:16